August 8, 2020
AliExpress WW

In Germany, 28 coronavirus neutralizing antibodies were isolated

AliExpress WW
Researchers at the University of Cologne Hospital and the German Center for Infection Research (DZIF), led by Professor Florian Klein, have found 28 antibodies that neutralize SARS-CoV-2. The results of the work appeared recently in the journal Cell. Clinical trials should begin by the end of this year.

According to Klein, the purpose of the work is to understand how the immune response to coronavirus SARS-CoV-2, and to identify potent antibodies that could be used for the prevention and treatment of coronavirus disease.

AliExpress WW

A team of scientists from Marburg, Frankfurt, Munich, Tubingen and Israel searched for antibodies to SARS-CoV-2 in 12 people who managed to defeat the coronavirus infection. They studied over four thousand SARS-CoV-2 – specific B cells – at the level of individual molecules and were able to partially decode the immune response (by producing Ig immunoglobulins to a foreign antigen) to coronavirus.

Researchers reconstructed 255 antibodies, which were then tested in the laboratory of Professor Stefan Becker in Marburg for their ability to neutralize SARS-CoV-2. 28 of them reached the final.

It was hoped that the vaccine would help provide quick protection against infection. In addition to preventing infection and directly treating patients with Covid-19, antibodies can be used for prophylaxis after exposure to an infected person.

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