- Ingrid Torjesen
- London, Great Britain
Two quick reviews by public health agencies in England showed that there was insufficient data to determine whether vitamin D supplementation could lower the risk of respiratory tract infections, including Covid-19.
Two weeks ago, Public Health of England commissioned the Scientific Advisory Commission on Nutrition (SACN) to examine new evidence of whether vitamin D supplements could reduce the risk of acute respiratory infections, while at the same time, the National Institute of Health and Health (NICE) began reviewing new data about vitamin D and the prevention and treatment of covid-19.1
The SACN review evaluated vitamin D and acute respiratory infections other than covid-19, published since its last review in 2016, and concluded that the available data do not support the need for vitamin D supplementation to prevent acute respiratory infections ways in the UK as a whole. Population. 2 Evaluated evidence included a widely cited systematic review and meta-analysis published in Bmj in 2017, which reported some benefits.
One of the authors of the BMJ review, Adrian Martino, a professor of respiratory infection and immunity at Queen Mary University of London, said the SACN rightly emphasized that the results of the five subsequent randomized controlled trials that they identified were mixed. But he added that the SACN did not try to analyze the combined test data and did not consider several other seemingly important tests.
“My group is in the final stages of an updated meta-analysis, including data from new trials identified by SACN, as well as nine others. We hope to present our findings next month, ”he said.
A brief review of NICE facts specifically examined new evidence on the role of vitamin D in relation to covid-19, and concluded that there is currently no evidence to support vitamin D supplementation that reduces the risk or severity of developing covid-19.4.
Agency researchers evaluated five observational studies of Vitamin D and Covid-19, published June 18, 2020 or earlier, and stated that they all had a high risk of bias due to the very poor quality of evidence. There are currently no data on clinical trials.
Martino said: “Vitamin D enthusiasts will point to a large number of other studies on pre-print sites that were not included in this review. However, these studies have not yet been peer-reviewed, so their results should not be relied upon in determining clinical practice or public health policies. The report does not comment on the need for vitamin D and covid-19 studies. ”
Paul Crisp, director of the Center for Guidelines at NICE, said: “We know that research on this issue is ongoing, and NICE continues to track new published evidence.”
The third brief review, a preprint from the Royal Society, concluded that vitamin D deficiency is associated with an increased risk of respiratory viral infections and that it is “biologically plausible” that vitamin D deficiency may contribute to susceptibility to Covid-19 infection, because such a deficiency can cause a violation immune regulation, which can reduce the first line of defense against covid-19.5. He encourages the government to provide more public information on current vitamin D recommendations and to conduct additional research on vitamin D deficiency can increase the risk of developing Covid-19 in the elderly and blacks, Asians and ethnic minorities (BAME).
In April, the government updated its vitamin D supplementation guidelines to protect bone and muscle health, urging everyone to take a 10 microgram daily supplement to mitigate the effects of reduced outdoor time due to blockage. The benefits of supplements are emphasized for people from black and ethnic minorities who may not receive enough vitamin D from sunlight.
A 2016 SACN review recommended further research on “Are There Differences in Vitamin D Consumption in Ethnic Diet in the UK?”
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